对无症状性中重度颈内动脉狭窄患者风险决策特点的研究
A study on the characteristics of risk decision-making in patients with asymptomatic moderate to severe inter-nal carotid artery stenosis
杨可璠 1毛善平1
作者信息
- 1. 430060 武汉大学人民医院神经内科
- 折叠
摘要
目的 探讨无症状性颈动脉狭窄(Asymptomatic carotid artery stenosis,AC AS)患者在风险条件下的决策特点.方法 应用简易智能精神状态检查量表(Mini-mental state examination,MMSE)、蒙特利尔认知评估量表(Montreal cognitive assessment,MoCA)、画钟试验(Clock drawing test,CDT)、词语流畅性试验(Verbal fluency task,VFT)、贝克抑郁量表(Beck depression inventory,BDI)、贝克焦虑量表(Beck anxiety inventory,BAI)评估25例ACAS患者以及与其年龄、性别、受教育年限相匹配的21例健康受试者的整体认知功能、执行功能、语言功能和焦虑抑郁情况;骰子博弈任务(Game of dice dest,GDT)评估这些受试者在风险条件下的决策功能.结果 在GDT任务中ACAS组与健康对照组比较,其更倾向于选择风险选项次数(z＝-5.26,P＜0.001),而健康对照组更易于选择安全选项次数(z=5.22,P＜0.001).与ACAS组比较,健康对照组更易于在选择风险选项输钱后转而选择安全选项,即负反馈利用率更高(z=3.97,P＜0.001).健康对照组相较ACAS组而言,盈利机会更大(t＝-6.64,P＜0.001).ACAS组风险选项次数与负反馈利用率呈负相关(r=-0.89,P＜0.001).结论 ACAS患者在风险条件下更倾向于做出风险决策.
Abstract
Objective To investigate the decision-making characteristics of patients with asymptomatic carotid artery stenosis(ACAS)under risk conditions.Methods Mini-Mental State Examination(MMSE),Montreal Cognitive Assessment(MoCA),Clock drawing test(CDT),Verbal fluency task(VFT),Beck De-pression Scale(Beck)were applied The Depression Inventory(BDI)and the Beck Anxiety Inventory(BAI)as-sessed the overall cognitive function,executive function,language function,and anxiety and depression of 25 patients with ACAS and 21 healthy subjects matched their age,sex,and years of education.The Game of dice dest(GDT)assessed the decision-making function of these subjects under risk conditions.Results Compared with the healthy control group,ACAS was more likely to choose the number of risky options(z=-5.26,P＜0.001)compared with the healthy control group,while the healthy control group was more likely to choose the safe option(z=5.22,P＜0.001),and the difference was statistically significant.Compared with the ACAS group,the healthy control group was more likely to switch to the safe option after losing money in the risk option,that is,the negative feedback utilization rate was higher(z=3.97,P＜0.001),and the difference was statistically significant.Compared with the ACAS group,the healthy control group had a greater profit opportunity(t=-6.64,P＜0.001),and the difference was statistically significant.The number of risk op-tions in the ACAS group was negatively correlated with negative feedback utilization(r=-0.89,P＜0.001).Conclusion Patients with ACAS are more likely to make risk decisions under risk conditions.
关键词
无症状颈动脉狭窄/风险决策/认知功能/骰子博弈任务Key words
Asymptomatic carotid artery stenosis/Risk decision-making/Cognitive function/Dice game tasks引用本文复制引用
出版年
2024
NETL
NSTL
万方数据