首页|Microarray expression analysis of epithelial ovarian cancer with distinct differentiation
Microarray expression analysis of epithelial ovarian cancer with distinct differentiation
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To identify gene expression profiling in epithelial ovarian cancer and to explore its correlation with histopathology characterization and prognosis. Gene expression profiles were generated from 10 human ovarian frozen tissue specimens using Agilent Human 1A microarrays. Strikingly, clear differences of gene expression patterns were observed in ovarian cancer as compared to normal tissues. Unique gene profiles were observed in moderately and poorly differentiated epithelial ovarian cancer. It is concluded that different histopathology characterization likely exists extensive molecular heterogeneity.
ovarian cancermicroarraydifferentiation
LI Yan-hong、ZHANG Wei、ZHU Shao-jun、YIN Guo-wu、YAN Kai-lin、ZHAO Hong-xi
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Department of Obstetrics and Gynaecology, Tangdu Hospital, Fourth Military Medical University, Xi'an 710038, China