首页|Comparison of concentration and health risks of 9 Fusarium mycotoxins in commercial whole wheat flour and refined wheat flour by multi-IAC-HPLC

Comparison of concentration and health risks of 9 Fusarium mycotoxins in commercial whole wheat flour and refined wheat flour by multi-IAC-HPLC

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Multiple mycotoxins can contaminate foods simultaneously leading to increased risks for human health. To assess exposure and health risks of 9 mycotoxins, we employed a multiple immunoaffinity column - high performance liquid chromatography method to determine their concentrations of 35 whole wheat flour and 50 refined wheat flour samples from China. The recoveries of the validated method were 75.78-118.24%, and the limits of detection and quantification were 1.5-20 and 5.0-60 mu g kg(-1), respectively. Multiple mycotoxins were detected in 37.1% of whole wheat flour and 8% of refined wheat flour. In the worst-case scenario, the hazard index was 222.69% for male and 253.97% for female with a cumulative exposure to Fusarium mycotoxins through consuming whole wheat flour, and deoxynivalenol was the main mycotoxin detected. In conclusion, whole wheat flour should be regarded with more health concern because of cumulative effects of co-occurred mycotoxins.

Fusarium mycotoxinsDerivativesWheat flourHealth riskIAC-HPLC

Zhang, Yingyue、Pei, Fei、Fang, Yong、Li, Peng、Zhao, Yan、Shen, Fei、Zou, Yanyu、Hu, Qiuhui

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Chinese Acad Agr Sci, Key Lab Agroprod Qual & Safety, Inst Qual Stand & Testing Technol Agroprod, Key Lab Agroprod, Beijing 100081, Peoples R China

Nanjing Univ Finance & Econ, Collaborat Innovat Ctr Modern Grain Circulat & Sa, Key Lab Grains & Oils Qual Control & Proc, Coll Food Sci & Engn, Nanjing 210023, Jiangsu, Peoples R China

2019

Food chemistry

Food chemistry

EI
ISSN:0308-8146
年,卷(期):2019.275(Mar.1)
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