Back in 2008, IWA Publishing released the book ’Water Management in Large River Basins’, edited byMilan A. Dimkić, Heinz-Jürgen Brauch and Michael Kavanaugh. The book was well received in a largenumber of countries.However, there have been many changes on our planet in the past 12 years. Global population continuesto grow, but while it is virtually exploding in some parts of the world, it is declining elsewhere. This ishaving a major impact on the global economy and, consequently, on macro geopolitics. Stability appearsto be on the downslope. People are migrating, largely because of wars but also due to major economicand political disparities. Climate and climate change are part of the counterpoint. While my associatesand I are finalizing this book, the COVID-19 pandemic is a threat to the global population and economy.