首页|Antiviral Effect of Ferula Plants and their Potential for Treatment of COVID-19: A Comprehensive Review

Antiviral Effect of Ferula Plants and their Potential for Treatment of COVID-19: A Comprehensive Review

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  • NETL
  • NSTL
  • Bentham Science Publ Ltd
Viral diseases have always been a threat to mankind throughout history, and many people have lost their lives due to the epidemic of these diseases. In recent years, despite the progress of science, we are still witnessing a pandemic of dangerous diseases such as COVID-19 all over the world, which can be a warning for humanity. Ferula is a genus of flowering plants commonly found in Central Asia, and its species have shown antiviral activity against a variety of viruses, including respiratory syncytial virus, Herpes simplex virus type 1, influenza, human immunodeficiency virus, hepatitis B, and coronaviruses. In this study, we intend to review the antiviral effects of Ferula plants, emphasizing the therapeutic potential of these plants in the treatment of COVID-19. Google, PubMed, Web of Science, and Scopus databases were searched to review the relevant literature on the antiviral effect of Ferula or its isolated compounds. The search was performed using the keywords Ferula, antiviral, Coronaviruses, respiratory syncytial virus, Herpes simplex virus type 1, influenza, human immunodeficiency virus, and hepatitis B. According to the reviewed articles and available scientific evidence, it was determined that the plants of this genus have strong antiviral effects. Also, clinical studies have shown that some species, such as Ferula assa-foetida, can be used effectively in the treatment of COVID-19. Ferula plants have inhibitory effects on various viruses, making them an attractive alternative to conventional antiviral agents. Therefore, these plants are a natural source of valuable compounds that can help us fight infectious diseases.

FerulaCoronavirusesrespiratory syncytial virusHerpes simplex virus type 1influenzahuman immunodeficiency virushepatitis B

Raziyeh Mohammadi、Hasan Forouzanfar、Hossein Rahimi、Seyed-Mahdi Mohamadi-Zarch、Khadijah Jamhiri、Seyyed Majid Bagheri

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Department of Medical-Surgical Nursing, School of Nursing and Midwifery, Sabzevar University of Medical Sciences, Sabzevar, Iran

Department of Nursing, Tabas School of Nursing, Birjand University of Medical Sciences, Birjand, Iran

Faculty of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran

Department of Physiology, Shahid Sadoughi University of Medical Sciences, Yazd, Iran

Shahid Faghihi Hospital, Shiraz University of Medical Sciences, Shiraz, Iran

Department of Physiology, Shahid Sadoughi University of Medical Sciences, Yazd, Iran||Neuroendocrine Research Center, Faculty of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran

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2025

10.2174/0113892010285343240530040218

Current pharmaceutical biotechnology

Current pharmaceutical biotechnology

SCI
ISSN：1389-2010
年,卷(期)：2025.26(8)
  • 93