首页|Chromatin profiling of coronary artery illuminates genetic risk for heart disease

Chromatin profiling of coronary artery illuminates genetic risk for heart disease

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A large-scale single-nucleus chromatin accessibility profiling study in coronary artery samples from patients with coronary artery disease generated a landscape of the regulatory activity during the disease。 These data highlight cell type-specific gene programs that can improve the interpretation of human genome-wide association studies findings for cardiovascular diseases。

Fish, Jason

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Univ Toronto

2022

Nature Genetics

Nature Genetics

SCI
ISSN:1061-4036
年,卷(期):2022.54(6)
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