首页|Immunohistochemical Characteristics of Spindle Cell Ameloblastic Carcinoma in a Horse

Immunohistochemical Characteristics of Spindle Cell Ameloblastic Carcinoma in a Horse

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? 2022 The Author(s)A 2-year-old male Thoroughbred horse presented with a mass in the maxilla. The focally ulcerated mass, approximately 8 cm in diameter, covered the upper left intermediate and corner incisor teeth (nos. 602 and 603 according to the modified Triadan system) and radiographic examination revealed displacement and lysis of the incisors. Histologically, the tumour was composed of a dense proliferation of spindle-shaped cells and neoplastic odontogenic epithelial cells arranged in island, follicular, plexiform or sheetlike patterns. The spindle-shaped cells were immunopositive for cytokeratins AE1/AE3, 5/6, 14 and 19. The Ki-67 index was 32.6% in the spindle cell component. Based on the histological and immunohistochemical findings, the tumour was diagnosed as spindle cell ameloblastic carcinoma.

Ameloblastic carcinomahorseproliferation markers

Ochi A.、Kishi D.、Ueno T.、Nukada T.、Nishioka T.、Kurimoto S.

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Equine Research Institute Japan Racing Association

Racehorse Clinic Ritto Training Center Japan Racing Association

2022

Journal of Comparative Pathology

Journal of Comparative Pathology

ISTP
ISSN:0021-9975
年,卷(期):2022.196
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