Synthesis, characterization, antibacterial evaluation and molecular docking study of 4-{[4-(5-phenyl-1,3,4-oxadiazol-2-yl)phenoxy]methyl}benzonitrile derivatives

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原文链接

NSTL

外文摘要：Novel series of 1,3,4-oxadiazole derivatives were synthesized by the reaction between respective acid hydrazides with various aldehydes using chloramine-T (CAT). The structural characterization of compounds 7a-e were confirmed by LC-MS and H-1 NMR, C-13 NMR spectroscopy and they were subjected for biological evaluation and molecular docking studies. The synthesized compounds exhibited comparable activity with the standard.

外文关键词：

Oxadiazolemolecular dockingantibacterialchloramine-T

作者：

Krishnaveni, T. C.、Kotian, Sumana Y.、Abishad, P. M.、Byrappa, K.、Rai, K. M. Lokanatha

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作者单位：

Univ Mysore, Yuvarajas Coll, Dept Chem, Mysuru 570005, Karnataka, India

Univ Mysore, Dept Studies Chemsitry, Mysuru 570006, Karnataka, India

Univ Mysore, Ctr Mat Sci & Technol, Mysuru 570006, Karnataka, India

Adichunchanagiri Univ, NH 75, Mandya 571481, Karnataka, India

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出版年：

2020

Journal of the Indian Chemical Society

CCR

ISSN：0019-4522

年,卷(期)：2020.97(5)