首页|A simple hydrazone probe for recognition of Al3+ and PPi and its applicability in lysosomal imaging
A simple hydrazone probe for recognition of Al3+ and PPi and its applicability in lysosomal imaging
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NSTL
Elsevier
A simple hydrazone probe (1) was designed and synthesized for the successive detection of Al3+ and pyrophosphate (PPi) in almost 100% buffer environment. The probe provided O2N donor set for chelation with Al3+, leading to a distinct fluorescence boost at 510 nm. The in-situ formed 1-Al3+ complex detected PPi with an "on-off" behavior. The detection limits for Al3+ and PPi were 35.7 nM and 76 nM, respectively. Benefiting from the existence of morpholine as lysosome-targeting group, probe 1 was successfully applied to the detection of Al3+ and PPi in lysosomes. (C) 2021 Elsevier B.V. All rights reserved.
NSTL
Elsevier
