首页|Methyl-linked Pyrazoles: Synthetic and Medicinal Perspective

Methyl-linked Pyrazoles: Synthetic and Medicinal Perspective

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Pyrazoles, an important and well-known class of the azole family, have been found to show a large number of applications in various fields, especially medicinal chemistry. Pyrazole derivatives, particularly methyl-substituted pyrazoles, have been reported as potent medicinal scaffolds that exhibit a wide spectrum of biological activities. The present review is an attempt to highlight the detailed synthetic approaches for methyl-substituted pyrazoles along with an in-depth analysis of their respective medical significances till March 2021. It is hoped that literature sum-up in the form of present review article would certainly be a great tool in assisting medicinal chemists in generating new leads possessing pyrazole nucleus with high efficacy and less microbial resistance.

Pyrazolesdrug discoverymedicinal chemistryorganic synthesismicrobial resistanceNMR spectral characteristics.

Bijender Singh、Ramesh Kataria、Vinod Kumar、Tulika Sharma、Joginder Singh

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2022

Mini reviews in medicinal chemistry

Mini reviews in medicinal chemistry

ISSN:1389-5575
年,卷(期):2022.22(5)
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