首页|The 1st year of the COVID-19 epidemic in Estonia: a population-based nationwide sequential/consecutive cross-sectional study

The 1st year of the COVID-19 epidemic in Estonia: a population-based nationwide sequential/consecutive cross-sectional study

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Objectives: The objective of this study was to assess the population prevalence of SARS-CoV-2 and changes in the prevalence in the adult general population in Estonia during the 1st year of COVID-19 epidemic. Study design: This was a population-based nationwide sequential/consecutive cross-sectional study. Methods: Using standardised methodology (population-based, random stratified sampling), 11 cross-sectional studies were conducted from April 2020 to February 2021. Data from nasopharyngeal testing and questionnaires were used to estimate the SARS-CoV-2 RNA prevalence and factors associated with test positivity. Results: Between April 23, 2020, and February 2, 2021, results were available from 34,915 individuals and 27,870 samples from 11 consecutive studies. The percentage of people testing positive for SARS-CoV-2 decreased from 0.27% (95% confidence interval [CI] = 0.10%-0.59%) in April to 0.04% (95% CI = 0.00%-0.22%) by the end of May and remained very low (0.01%, 95% CI = 0.00%-0.17%) until the end of August, followed by an increase since November (0.37%, 95% CI = 0.18%-0.68%) that escalated to 2.69% (95% CI = 2.08%-2.69%) in January 2021. In addition to substantial change in time, an increasing number of household members (for one additional odds ratio [OR] = 1.15, 95% CI = 1.02-1.29), reporting current symptoms of COVID-19 (OR = 2.21, 95% CI = 1.59-3.09) and completing questionnaire in the Russian language (OR 1.85, 95% CI 1.15-2.99) were associated with increased odds for SARS-CoV-2 RNA positivity. Conclusions: SARS-CoV-2 population prevalence needs to be carefully monitored as vaccine programmes are rolled out to inform containment decisions. (C) 2022 The Author(s). Published by Elsevier Ltd on behalf of The Royal Society for Public Health.

COVID-19SARS-CoV-2PrevalenceSurveillanceEpidemiologyHealth inequalitiesEstoniaSARS-COV-2PREVALENCEAPRIL

Uuskula, A.、Kalda, R.、Solvak, M.、Jurisson, M.、Kaarik, M.、Fischer, K.、Keis, A.、Raudvere, U.、Vilo, J.、Peterson, H.、Kaarik, E.、Metspalu, M.、Jurgenson, T.、Kolberg, L.、Tiit, E-M、Vassil, K.、Milani, L.

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Inst Family Med & Publ Hlth,Univ Tartu

Johan Skytte Inst Polit Studies,Univ Tartu

Inst Math & Stat,Univ Tartu

Inst Comp Sci,Univ Tartu

Inst Genom,Univ Tartu

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2022

Public health

Public health

SCI
ISSN:0033-3506
年,卷(期):2022.205
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