查看更多>>摘要：Angioplasty with stenting is one of the primary treatment for coronary artery disease, hence, performance of the stent is deemed important. Bioabsorbable stents are the new generation of stents. Bioabsorbable magnesium alloys are a promising solution for adverse effects of long-term usage of stents. While their corrosion mechanics and biocom-patibility have extensively been studied, there are no studies on application of functionally graded materials (FGM) on reduction of dogboning in bioabsorbable stents.
查看更多>>摘要：The purpose of this study was to evaluate the relationship between the breath-holding duration and the sensitivity of the arterial baroreflex, as well as the prognostic value of the breath-holding test in the assessment of decreased baroreflex sensitivity (BRS) in patients with chronic heart failure (CHF).
Thessa I.M. HilgenkampSang Ouk Wee Elizabeth C. SchroederTracy BaynardBo Femhall...
6页
查看更多>>摘要：Individuals with Down syndrome (DS) experience autonomic dysfunction, with reduced sympathetic and parasympathetic control. This results in alterations in resting heart rate and blood pressure and attenuated responses to sympathoexcitatory stimuli. It is unknown to what extent this impacts the regulation of peripheral blood flow in response to sympathetic stimuli, which is an important prerequisite to exercise and perform work. Therefore, we aimed to investigate differences in peripheral blood flow regulation in response to lower body negative pressure (LBNP) between individuals with and without DS Methods: Participants (n = 10 males with DS and n = 11 male controls, mean age 23.7 years ± 3.2) underwent 5 min of LBNP stimulations (-20 mmHg), after resting supine for 10 min. One minute steady state blood pressure and blood flow at baseline and during LBNP were obtained for analysis. Mean flow velocity and arterial diameters were recorded with ul-trasonography; foreram blood flow (FBF), shear rate and forearm vascular conductance (FVC) were calculated using brachial blood pressure measured right before ultrasound recordings Results: Participants with DS responded differently (consistent with reduced vasoconstrictive control) to the LBNP stimulus (significant ConditionxGroup interaction effect) for mean velocity (p = 0.02), FBF (p = 0.04), shear rate (p = 0.02) and FVC (p = 0.03), compared to participants without DS.
查看更多>>摘要：Physiology Research Center, Institute of Basic and Clinical Physiology Sciences and Department of Physiology and Pharmacology, Afzalipour Faculty of Medicine, Kerman University of Medical Sciences, Kerman, Iran
查看更多>>摘要：Coronary heart diseases are inversely related to plasma high-density lipoprotein (HDL) level. Paraoxonase-1 (PON1) is mainly associated with HDL and plays a vital role in protection of low-density lipoprotein (LDL) and HDL. The aim of this study was to investigate the association between paraoxonase activity (PON1) with lipid profile, apoA-I, apoB and apoB/apoA-I ratio in subjects with different level of HDL cholesterol (HDL-C). Methods: 135 subjects, 20—60 years old, contributed to this study. The subjects were divided into three groups (45 in each group) with different levels of HDL-C (High, Normal and Low). For each group, the activity of PON1 was measured using paraoxon as a substrate. Moreover, the serum level of lipid profile, ApoA and apoB were measured. The statistical analysis was performed using SPSS software.
查看更多>>摘要：This study aimed to investigate the relationship between blood pressure variability and the incidence of silent cerebral infarction (SCI) in patients with primary hypertension.
查看更多>>摘要：So far, in the stress calculation of the plaques, the blood has been simulated as a single component, and the role of the mechanical interaction between the red blood cells (RBCs), white blood cells (WBCs), and plasma with that of the plaque has been neglected. This study was aimed at proposing an interactive method based on smoothed particle hydrodynamics (SPH), a fully mesh-free particle approach, to simulate the blood as a fluid with free surfaces, including the RBC, WBC, and plasma, to determine the vulnerable plaque on a basis of the induced stresses.
查看更多>>摘要：Dear readers, authors and reviewers, as those of you who attended ARTERY 18 will already know, this is unfortunately the final issue of Artery Research that will be supported by Elsevier. I would therefore like to take this opportunity to thank all at Elsevier for their support over the years which has led to Artery Research gaining, a long overdue, impact factor and establishing itself as a 'natural home' for papers relating to arterial structure and physiology.
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