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科学通报(英文版)
科学通报(英文版)

周光召

旬刊

1001-6538

csb@scichina.com

010-64036120

100717

北京东黄城根北街16号

科学通报(英文版)/Journal Chinese Science BulletinEISCI
查看更多>>《科学通报》创刊于1950年,是中国科学院主办、中国科学杂志社承办的自然科学综合性学术刊物,报道自然科学各学科基础理论和应用研究方面具有创新性和和高水平的、具有重要意义的最新研究成果,要求文章的可读性强,能在一个比较宽范的学术领域产生深刻的影响。我们的目标是:成为国内外读者了解中国乃至世界范围的自然科学各研究领域最新成果的主要窗口之一。《科学通报》进入了国际上主要检索系统,如CA,EI,日本《科技速报》和美国科学信息研究所(ISI)的以下系统:Science Citation Index(SCI-CDE),SCISearch,Current Contents(PC&E)和Research Alert。
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    Neolithization of Dawenkou culture in the lower Yellow River involved the demic diffusion from the Central Plain

    Fen WangRui WangHao MaWen Zeng...
    3677-3681页

    An efficient electrode for reversible oxygen reduction/evolution and ethylene electro-production on protonic ceramic electrochemical cells

    Yangsen XuKang XuHua ZhangFeng Zhu...
    3682-3691页
    查看更多>>摘要:Protonic ceramic electrochemical cells(PCECs)have demonstrated great promise for applications in the generation of electricity,and the synthesis of chemicals(for example,ethylene).However,enhancing the electrochemical reactions kinetics and stability of PCECs electrodes is one grand challenge.Here,we pre-sent a novel electrode material via a co-doping of cesium(Cs)and niobium(Nb)on PrBaCo2O6_δ with the composition of PrBao,9Cso.iCo1.9Nbo.1O6_δ(PBCCN),which naturally decomposes into dual phases of a double-perovskite PBCCN(DP-PBCCN,~92.3 wt%)and a single-perovskite Bao.9Cso.1Coo.95Nbo.o5O3_i(SP-BCCN,~7.7 wt%)under typical powder processing conditions.PBCCN exhibits a low area-specific resistance(ASR)value of 0.107 Ω cm2,an outstanding performance of 2.04 W cm-2 in fuel cell(FC)mode,a current density of-2.84 A cm-2 at 1.3 V in electrolysis cell(EC)mode,and promising reversible oper-ational durability of 53 cycles in~212 h at+/-0.5 A cm-2 and 650 ℃.Cs doping generates more oxygen vacancies and accelerates the oxygen exchange kinetics,while Nb doping effectively enhances the stabil-ity,as illustrated by the analyses of X-ray photoelectron spectroscopy,and electrical conductivity relax-ations.When applied as the positrode for electrochemical non-oxidative dehydrogenation of ethane(C2H6)to ethylene(C2H4)on PCECs,it displays an encouraging C2H6 conversion of 12.75%and a C2H4 selectivity of 98.4%at 1.2 V.

    Facile formation of van der Waals metal contact with Ⅲ-nitride semiconductors

    Xiyu SunDanhao WangXiaojing WuJiahao Zhang...
    3692-3699页
    查看更多>>摘要:Metal-semiconductor contacts play a pivotal role in controlling carrier transport in the fabrication of modem electronic devices.The exploration of van der Waals(vdW)metal contacts in semiconductor devices can potentially mitigate Fermi-level pinning at the metal-semiconductor interface,with partic-ular success in two-dimensional layered semiconductors,triggering unprecedented electrical and optical characteristics.In this work,for the first time,we report the direct integration of vdW metal contacts with bulk wide bandgap gallium nitride(GaN)by employing a dry transfer technique.High-angle annular dark-field scanning transmission electron microscopy explicitly illustrates the existence of a vdW gap between the metal electrode and GaN.Strikingly,compared with devices fabricated with electron beam-evaporated metal contacts,the vdW contact device exhibits a responsivity two orders of magni-tude higher with a significantly suppressed dark current in the nanoampere range.Furthermore,by lever-aging the high responsivity and persistent photoconductivity obtained from vdW contact devices,we demonstrate imaging,wireless optical communication,and neuromorphic computing functionality.The integration of vdW contacts with bulk semiconductors offers a promising architecture to overcome device fabrication challenges,forming nearly ideal metal-semiconductor contacts for future integrated electronics and optoelectronics.

    Essentiality of SLC7A11-mediated nonessential amino acids in MASLD

    Jie ShenEnjun XieShuying ShenZijun Song...
    3700-3716页
    查看更多>>摘要:Metabolic dysfunction-associated steatotic liver disease(MASLD)remains a rapidly growing global health burden.Here,we report that the nonessential amino acid(NEAA)transporter SLC7A11 plays a key role in MASLD.In patients with MASLD,we found high expression levels of SLC7A11 that were correlated directly with clinical grade.Using both loss-of-function and gain-of-function genetic models,we found that Slc7al 1 deficiency accelerated MASLD progression via classic cystine/cysteine deficiency-induced ferroptosis,while serine deficiency and a resulting impairment in de novo cysteine production were attributed to ferroptosis-induced MASLD progression in mice overexpressing hepatic Slc7a11.Consistent with these findings,we found that both serine supplementation and blocking ferroptosis significantly alleviated MASLD,and the serum serine/glutamate ratio was significantly lower in these pre-clinical disease models,suggesting that it might serve as a prognostic biomarker for MASLD in patients.These findings indicate that defects in NEAA metabolism are involved in the progression of MASLD and that serine deficiency-triggered ferroptosis may provide a therapeutic target for its treatment.

    Atmospheric oxygenation as a potential trigger for climate cooling

    Guang-Yi WeiGaojun Li
    3717-3722页
    查看更多>>摘要:Secular changes in atmospheric CO2 and consequent global climate variations,are commonly attributed to global outgassing and the efficiency of silicate weathering,which may have been linked to mountain formation,land/arc distribution,and plant colonization through geological time.Although oxidative weathering has been shown to exert a significant role in the propagation of weathering fronts through the oxidation of Fe-bearing minerals,the influence of atmospheric O2 concentration(pO2)on silicate weathering,CO2 consumption,and global climate has not been thoroughly evaluated.This study presents a numerical model aimed at estimating the effects of pO2 on the climate,considering the influence of pO2 on the regolith thickness and thus weathering duration of granitic domains.Our model simulations reveal that an increase in weathering efficiency,through deeper penetration of the oxidative weathering front in the granitic regolith,would independently introduce a steady-state climate cooling of up to~8 ℃,in step with one-order of magnitude rise in pO2.This temperature change may have repeatedly initiated the run-away ice-albedo feedback,leading to global glacial events(e.g.,Neoproterozoic Snowball Earth).Increasing granitic weathering efficiency caused by a substantial pO2 increase may also have contributed to the development of icehouse climate during the Phanerozoic.

    Higher water content observed in smaller size fraction of Chang'e-5 lunar regolith samples

    Honglei LinRui XuShuai LiRui Chang...
    3723-3729页
    查看更多>>摘要:Water has been detected in lunar regolith,with multiple sources identified through the analysis of indi-vidual grains.However,the primary origin of water in the bulk lunar regolith remains uncertain.This study presents spectroscopic analyses of water content in sealed Chang'e-5 samples.These samples were sieved into various size fractions(bulk,<45 pm,and 45-355 pm)inside a glovebox filled with high-purity nitrogen.Results indicate a higher water content in the fine fractions(~87±11.9 ppm)than in bulk soil(~37±4.8 ppm)and coarse fractions(~11±1.5 ppm).This suggests that water is predominantly concen-trated in the outermost rims of the regolith grains,and thus exhibits dependence on the surface volume ratio(also known as surface correlation),indicating solar wind is a primary source of lunar surface water.Laboratory,in-situ,and orbital results bridge sample analysis and remote sensing,offering a cohesive understanding of lunar surface water characteristics as represented by Chang'e-5.The discovery provides statistical evidence for the origin of water in lunar soil and can be considered representative of the lunar surface conditions.The water enrichment of the finest fraction suggests the feasibility of employing size sorting of lunar soils as a potential technological approach for water resource extraction in future lunar research stations.

    Recent progress of flexible rechargeable batteries

    Xiao ZhuHaoran ZhangYongxin HuangEr He...
    3730-3755页
    查看更多>>摘要:The rapid popularization of wearable electronics,soft robots and implanted medical devices has stimu-lated extensive research in flexible batteries,which are bendable,foldable,knittable,wearable,and/or stretchable.Benefiting from these distinct characteristics,flexible batteries can be seamlessly integrated into various wearable/implantable devices,such as smart home systems,flexible displays,and implanta-ble sensors.In contrast to conventional lithium-ion batteries necessitating the incorporation of stringent current collectors and packaging layers that are typically rigid,flexible batteries require the flexibility of each component to accommodate diverse shapes or sizes.Accordingly,significant advancements have been achieved in the development of flexible electrodes,current collectors,electrolytes,and flexible structures to uphold superior electrochemical performance and exceptional flexibility.In this review,typical structures of flexible batteries are firstly introduced and classified into mono-dimensional,two-dimensional,and three-dimensional structures according to their configurations.Subsequently,five dis-tinct types of flexible batteries,including flexible lithium-ion batteries,flexible sodium-ion batteries,flexible zinc-ion batteries,flexible lithium/sodium-air batteries,and flexible zinc/magnesium-air batter-ies,are discussed in detail according to their configurations,respectively.Meanwhile,related comprehen-sive analysis is introduced to delve into the fundamental design principles pertaining to electrodes,electrolytes,current collectors,and integrated structures for various flexible batteries.Finally,the devel-opments and challenges of flexible batteries are summarized,offering viable guidelines to promote the practical applications in the future.

    The mechanisms,hallmarks,and therapies for brain aging and age-related dementia

    Shiyun JinWenping LuJuan ZhangLi Zhang...
    3756-3776页
    查看更多>>摘要:Age-related cognitive decline and dementia are significant manifestations of brain aging.As the elderly population grows rapidly,the health and socio-economic impacts of cognitive dysfunction have become increasingly significant.Although clinical treatment of dementia has faced considerable challenges over the past few decades,with limited breakthroughs in slowing its progression,there has been substantial progress in understanding the molecular mechanisms and hallmarks of age-related dementia(ARD).This progress brings new hope for the intervention and treatment of this disease.In this review,we categorize the latest findings in ARD biomarkers into four stages based on disease progression:Healthy brain,pre-clinical,mild cognitive impairment,and dementia.We then systematically summarize the most promis-ing therapeutic approaches to prevent or slow ARD at four levels:Genome and epigenome,organelle,cell,and organ and organism.We emphasize the importance of early prevention and detection,along with the implementation of combined treatments as multimodal intervention strategies,to address brain aging and ARD in the future.

    Now and future:Strategies for diagnosis,prevention and therapies for Alzheimer's disease

    Jiong ShiJacques TouchonLefkos T MiddletonMercé Boada Rovira...
    3777-3784页
    查看更多>>摘要:After a number of failed drug studies on Alzheimer's disease(AD)over the past decade,clinical trials of AD started to show encouraging results and were approved or pending approval for clinical use.However,controversies on the clinically meaningful benefits and risks of brain edema and microhemorrhages have reminded us to think further about monitoring treatment and developing new drug targets.The goal of this review is to find insights from clinical trials that aimed at two key pathological features of AD,i.e.,amyloid-p(Ap)and tau protein,and to explore other targets such as anti-inflammation in AD.The com-plex pathophysiology of AD may require combination therapies rather than monotherapy.Throughout the course of AD,multiple pathways are disrupted,presenting a multitude of possible therapeutic targets for designing prevention and intervention for AD.