查看更多>>摘要:Beilschmiedia is a pantropical genus of the Lauraceae family with more than 250 species. These plants are native to tropical Asia, Africa, Australia, New Zealand, Central America, Caribbean, and South America [1]. Extensive phytochemical investigations have been carried out on Beilschmiedia plants, which led to the isolation of numerous classes of secondary metabolites such as endiandric acid derivatives [2], lignans [3], neolignans [4], flavonoids [5], amides [6], alkaloids [7], and essential oils [8]. Beilschmiedia maingayi Hook.f. belongs to the Lauraceae family and is commonly known as 'empawang berok' in Malaysia. It grows in primary or secondary, hill, or montane forest, on yellowish or red clay soils, brownish soils, or loam soils with limestone [9]. In a continuation of our systematic studies on chemical constituents of Malaysian Beilschmiedia species [10], we have investigated the phytochemical study of the stem bark extracts of B. maingayi. As a result, five alkaloids, (+)-boldine (1) [11], (+)-norboldine (2) [12], (+)-cassythicine (3) [12], (+)-laurotetanine (4) [12], and (+)-N-methyIIaurotetanine (5) [13], together with five other compounds, vanillin (6) [4], vanillic acid (7) [4], (3-sitosterol (8) [4], p-sitostenone (9) [4], and taraxerol (10) [10], were successfully isolated. Their structures were established on the basis of spectroscopic analysis and chemical evidence. To the best of our knowledge, all compounds were isolated for the first time from this species.