首页期刊导航|Химия природных соединений
期刊信息/Journal information
Химия природных соединений
Редакция　журнала　'Химия　природных　соединений'
Химия природных соединений

Редакция　журнала　'Химия　природных　соединений'

0023-1150

Химия природных соединений/Journal Химия природных соединений
正式出版
收录年代

    CHEMICAL CONSTITUENTS WITH NITRIC OXIDE INHIBITION FROM THE FRUIT PEEL OF Annona squamosa

    Weifeng DaiYehua ZhangYanfang Liu
    3页
    查看更多>>摘要：Chemical research on plants is of great importance for the research and development of plants used as resources in many fields,especially regarding the non-edible and non-medicinal parts of plants.Previous investigations have shown that,compared with the chemicals and the bioactivity found in traditionally edible plants and the parts of plants used medicinally,many substances with new functions or known compounds with more activity have been found in the non-edible or non-medicinal parts of plants(1-3).It provides more possibilities for the comprehensive utilization and development of the whole plant.Annona squamosa L,is a deciduous tree in the genus Annona,family Annonaceae that grows in the tropics and is well known for its fruit(4).In China,the root of A.squamosa is used as a folk medicine to treat dysentery,depression,and some bone diseases(4),In recent years,as well as the fruit and roots,the chemicals and functions of many other parts of squamosa have been investigated.To date,more than 200 chemicals have been found from the roots,stem bark,leaves,fruit,fruit peel,and seeds of this plant,mainly annonaceous acetogenins,terpenes,alkaloids,cyclopeptides,and flavones,most of which have anticancer,anti-oxidant,antidiabetic,antihypertensive,hepatoprotective,antiparasitic,antimalarial,insecticidal,microbicidal,and molluscicidal activity(5).
      原文链接:
    • NSTL

    CHEMICAL CONSTITUENTS OF Cajanus cajan FLOWERS

    Xiao-Yu XuCheng-Xun LiAi-Ping Li
    2页
    查看更多>>摘要：Cajanus cajan(L.)Millsp.,a member of the genus Cajanus,family Leguminosae,is the only woody edible legume.In addition to food,С cajan is also used in traditional medicine.Previous investigation of С cajan leaves led to the isolation of active compounds such as stilbenes and flavonoids(1),as well as compounds with a variety of biological activities such as antioxidant(2),antibacterial(3),antimalarial(4),anticancer(5),anti-osteoporosis(6)and so on.However,the study of chemical constituents of С cajan flowers has not been reported yet.Hence,the phytochemical investigation of C.cajan flowers was carried out in the present work.The dried flowers of C.cajan(0.75 kg)were pulverized and extracted by heating with 95% ethanol before reflux.The extract was concentrated to give a residue(104 g),then suspended in water and successively partitioned with petroleum ether,dichloromethane,and/7-butanol.The dichloromethane fraction(4.0 g)was subjected to silica gel column chromatography with a gradient elution system of CH2Cl2-MeOH to obtain 15 subfractions,and further chromatographed over MCI,silica gel column,Sephadex LH-20,and preparation HPLC to yield compounds 1-7.
      原文链接:
    • NSTL

    TRITERPENOIDS,STEROIDS,AND OTHER CONSTITUENTS OF THE ROOTS OF Codonopsis pilosula

    Ru-Yue WangPan-Jie SuZhan-Xin Zhang
    2页
    查看更多>>摘要：Codonopsis is a dicotyledonous genus of perennial plants in the family Campanulaceae,including 42 species that are mainly distributed in Central,East,and South Asia,and with approximately 40 species can be found in China(1).The roots of Codonopsis pilosula(Franch.)Nannf,known as"Dang shen"in Chinese,is one of the most famous traditional Chinese medicines,which has been used for the treatment of body weakness,poor appetite,thirst,indigestion,chronic diarrhea,archoptoma,chronic anemia,and leukemia(2).It also has multiple biological activities,such as enhancing immunity and improving learning and memory(3).Furthermore,C.pilosula IS regarded as a kind of healthy food because it exhibits a range of uses,i.e.,as fat substitutes in low-calorie foods,and it also has disease-modifying effects,for instance,treating gastric uker(4).
      原文链接:
    • NSTL

    TRITERPENOIDS WITH CYTOTOXICITY FROM Abelia engleriana

    Xuanji XueJing ZhaoYanru Ma
    4页
    查看更多>>摘要：Abelia engleriana(Graebn.)Rehder is a plant used as a food ingredient and belongs to the Abelia genus of the Caprifoliaceae family(1,2).Jellies made from its leaves are famous snacks in Shaanxi Province,and the plant has extremely promising resources(3,4).However,research on these resources are few and often focused on pectin.Moreover,the chemical constituents and bioactivity of A,engleriana have not been reported.In this study,the chemical constituents of A,engleriana were isolated and purified,and their cytotoxicity was evaluated.Seventeen triterpenoids were obtained and identified.They were abruslactone A(1)(5),eupatoric acid(2)(6),3β-hydroxylup-9(11),12-dien-8-oic acid(3)(7),3β-hydroxy-urs-12-en-29p-oic acid(4)(8),3p-hydroxylup-12-en-28-oic acid(5)(9),methyl ursolate(6)(10),27-hydroxy-α-amyranol(7)(11),lanostan-3β-ol(8)(12),oleanolic acid(9)(13),3-hydroxy-11-ursene(10)(14),uvaol(11)(15),ursolic acid(12)(14),siaresinolic acid(13)(16),pomolic acid(14)(17),a-amyrin-3-O-β-D-glucopyranoside(15)(18),2a,3a-dihydroxy-urs-12-ene-28-ioc acid(16)(19),and 3-O-α-L-rhamnopyranosyl-(1→3)-β-D-xylopyranosyl-(1→3)-α-L-rhamnopyranosyl-(1→2)-a-L-arabinopyranosylhederagenin(17)(20).
      原文链接:
    • NSTL

    TiCl4-ЭФФЕКТИВНЫЙ КАТАЛИЗАТОР ПРЕВРАЩЕНИЯ БЕТУЛИНА В А-HEО-3-ИЗОПРОПИЛ-19β,28-ЭПОКСИ-18а-ОЛЕАН-9(10)-ЕН

    Р.P.СаяховН.И.МедведеваМ.П.Яковлева
    1页
    查看更多>>摘要：В последнее время все большее внимание химиков и фармакологов привлекает тритерпеноид бетулин(1),содержащийся(до 30%)в коре белой березы(Betula pendula Roth)и выделяемый из нее,поскольку проявляет широкий спектр активности-антисептическую,антирахитную,ранозаживляющую,гипохолестеринемическую,противовоспалительную,желчегонную,гепатопротекторную,включая анти-ВИЧ и противоопухолевое действие [1].
      原文链接:
    • NETL
    • NSTL

    ANTIMICROBIAL CYTOCHALASAN ALKALOIDS FROM AN ENDOPHYTIC FUNGUS Chaetomium globosum

    Jun-Fei WangRong HuangSi-Si Liu
    4页
    查看更多>>摘要：Endophytic fungi exist widely in healthy plant tissues.They are various and widely distributed and do not cause obvious disease symptoms(1,2).It is well known that endophytic fungi can produce a variety of novel structural compounds with antimicrobial,anti-tumor,antiviral,and other biological activities(3,4).Among them,the genus Chaetomium,as a prevalent endophytic group,is one of the important contributors.The secondary metabolites Irom Chaetomium species showed impressive chemical diversities.Chaetomium globosum,the most common species in Chaetomium,is regarded as a notable producer of chaetoglobosins and shows extensive bioactivities such as antitumor(5,6),antimicrobial(7,8),and phytotoxic activities(9).
      原文链接:
    • NSTL

    ISOQUINOLINE ALKALOIDS OF Ilex latifolia

    C.Y ChenС L.КаоН.С Yeh
    2页
    查看更多>>摘要：Ilex(Aquifoliaceae)species are distributed widely in the People's Republic of China,and some are used extensively in folk medicine.For example,Ilex rotunda is antipyretic and an antidote and is used for the treatment of the common cold,tonsillitis,and stomach and intestinal ukers.L pubescens is used for the treatment of coronary disease,myocardial infarction,dysentery,and erysipelas.L comuta and I.latifolia are used for the treatment of headache,toothache,bloodshot eyes,and tinnitus(1).Previous studies on the Ilex genus have led to the isolation of triterpenes,triterpene glycosides(2),hemiterpene glycosides(3),phenolic compounds(4),and flavonoids(5).In the present study on the chemical components of the leaves of Ilex latifolia Thunb.,13 compounds were isolated.A methanolic extract of the leaves of I.latifolia was concentrated to obtain a residue,and it was partitioned between CH2CI2 and H2O.The aqueous layer was extracted with n-BuOH.The n-BuOH layer was concentrated and subjected to chromatography.As a result,13 compounds,including nine isoquinoline alkaloids,northalifoline(1)(6),thalifoline(2)(6),corydaldine(3)(7),and N-methykoiydaldine(4)(8),oxyberberine(5)(9),berberine(6)(10),palmathe(7)(11),jatrorrhizine(8)(12),and columbamine(9)(13),and four benzenoids,p-hydroxybenzaldehyde(6),p-hydroxybenzoic acid(6),3,4-dimethoxy benzoic apid(6),and syringic acid(6)were isolated All of these compounds were isolated for the first time from this source.
      原文链接:
    • NSTL

    ONE STRAIN-MANY COMPOUNDS METHOD FOR PRODUCTION OF DIVERSE METABOLIC PROFILES USING Chaetomium sp.FROM Astragalus membranaceus

    Hongchi ZhangRui LiuYang Yang
    3页
    查看更多>>摘要：Previously,we found that the endophytic fungus AR-17-7 from the root of Astragalus membranaceus(Fisch.)Bunge associated with potato dextrose agar(PDA)media can produce structurally diverse chaetoglobosins.This encouraged further study on the use of the endophytic fungus AR-17-7 for the production of diverse metabolic profiles by the OSMAC technique.The OSMAC(one strain of many compounds)strategy,developed by Zeeck in the early 2000s,has been demonstrated to be a simple and effective method(1).In this strategy,the silent gene sequence was activated by changing culture conditions,including media composition,medium phase,and temperature(2).The OSMAC approach has been successfully applied to produce new secondary metabolites from single microbial strains during the last 10 years [3].
      原文链接:
    • NSTL

    CYCLIC PEPTIDE SECONDARY METABOLITES WITH ANTIFUNGAL ACTIVITY AGAINST ROOT-ROT PATHOGENS OF Panax notoginseng PRODUCED BY Streptomyces yatensis

    Xiao ChenJin-Mei ZouLei Li
    2页
    查看更多>>摘要：Panax notoginseng(Burkili)RH.Chen is an important medicinal plant for cardiovascular diseases; however,in the process of its growth,it is easily infected by harmful microorganisms.The root-rot disease of Panax notoginseng caused by pathogenic fungus such as Fusarium oxysporum,Fusarium solani,Plectosphaerella cucumerina,and Alternaria panax,etc.is the main factor in the continuous cropping obstacle of Panax notoginseng(1-3).As the most common genus in the environment of Actinomycetes,Streptomyces is the main contributor to the development of antifungal antibiotics(4,5).In the course of searching for antibiotics from the genus Streptomyces(6,7),strain YIM PH2O103 exhibited antifungal activities against some phytopathogenic fungi of root-rot diseases of Panax notoginseng.Herein we report on the cyclic peptide secondary metabolites with antifungal activity against root-rot pathogens of Panax notoginseng produced by the isolate YIM PH2O103.The producing strain YIM PH2O103 was isolated from a Panax notoginseng rhizosphere soil sample collected in WenShan County,Yunnan Province,China.It was identified as Streptomyces yatensis based on the morphological and phylogenetic analysis of its 165 rRNA gene sequence according to the method described previously(8).A voucher specimen was deposited in Yunnan Institute of Microbiology,Yunnan University,China.
      原文链接:
    • NSTL

    CHEMICAL COMPOSITION OF Livistona chinensis AND Areca catechu PALM NUTS

    E.E.EssienB.S.AntiaE.L Etuk
    2页
    查看更多>>摘要：Livistona chinensis(Jacq.)R.Br,ex Mart.,commonly known as Chinese Fan palm or Chinese Fountain palm,and Areca catechu L.(Betel palm)belong to the palm family(Arecaceae); they are widely distributed in the tropical and subtropical regions of the world(1,2).These palms are mainly cultivated for ornamental purposes and for use in herbal remedies.The food potential of L.chinensis nut has been evaluated by Nwosu(3),while A.catechu nut has a long history of consumption,especially in Southeast Asia(4).In Nigeria both seeds are not utilized due to lack of adequate information.Livistona chinensis seeds contain phenolic compounds and are used traditionally by the Chinese as an anticancer agent(1).Areca catechu is used in ethnomedicine for the treatment of ailments such as urinary infections,diarrhea,and foot sores,and as an antiparasitic agent(5).Areca catechu seeds contain several alkaloids belonging to the pyridine group; most important of them physiologically is arecoline(6).Thus,to our knowledge,there are no data on the amino acids,fatty acids,and mineral composition of L.chinensis kernels; however,a few reports are available on the composition of A,catechu seeds(2,7,8).Therefore,this study was conducted to evaluate the amino acids,fatty acids,and minerals composition of L,chinensis and A.catechu kernels.
      原文链接:
    • NSTL