首页期刊导航|中国化学快报（英文版）
期刊信息/Journal information
中国化学快报（英文版）
中国化学快报（英文版）

梁晓天

月刊

1001-8417

cclbj@imm.ac.cn

010-63165638

100050

北京市先农坛街1号

中国化学快报（英文版）/Journal Chinese Chemical LettersCSCDCSTPCD北大核心SCI
查看更多>>本刊是由中国科协主管、中国化学会主办、中国医学科学院药物所承办的学术期刊，是由著名化学家梁晓天院士主编。是中国化学界通向世界的窗口，内容覆盖化学全领域。本刊的办刊宗旨是“新、快、准”，我们将坚持这个宗旨，力求及时反映化学研究中各个相关领域内的最新进展及热点问题，主要读者群是科研人员、研究生、大学教师。现已被国内外多家数据库收录，如SCI　Search、Chemical Abstract、Research Alert、Chemistry Citation Index、《日本科技文献速报》、万方数据数字化期刊群、中国学术期刊过刊全文数据库、中国学术期刊（光盘版）、中国学术期刊文摘、中文期刊全文数据库、俄罗斯Рж期刊源等。
正式出版
收录年代

    Recent progresses of exosome-liposome fusions in drug delivery

    Lulu ZhengBo HuDeyao ZhaoWenjing Liu...
    107-117页
    查看更多>>摘要：Exosomes are membrane-bound nanoscale extracellular vesicles,which produced by almost all organisms.Due to the excellent biocompatibility,long circulation time as well as low immunogenicity,exosomes as naturally-derived drug delivery carriers have experienced explosive growth over the past decades.How-ever,issues such as insufficient loading efficiency,heterogeneous delivery efficiency,uncontrollable tar-geting ability,and low production limit their wide application.Recently,the emerging exosome-liposome fusion strategy has become a potential approach to solve such issues.Thus,this review mainly focuses on the currently developed exosome-liposome fusion strategy and their application in drug delivery as well as disease treatment.This review aims to shed light on the advantages of fusion strategy in drug delivery and provides a better understanding for more rational design.The current challenge and future perspective regarding their clinical translation and application will also be discussed.
      原文链接:
    • 万方数据
    • 维普

    Strategies and opportunities of micro/nano delivery systems for targeted therapy of ulcerative colitis:Focus on underlying mechanisms and future perspectives

    Zihan LiuHan LiuJialing ChengHongliang Wang...
    118-130页
    查看更多>>摘要：Ulcerative colitis(UC)is a common progressive inflammatory disease whose incidence has increased rapidly in recent years,and can develop into colorectal cancer in severe cases.There are currently no adequate or effective treatments for UC due to the fact that some patients have found suboptimal results after repeated administration,while others have experienced adverse effects.With the rapid development of nanotechnology,developing innovative colon-targeting platforms is essential to improving efficacy,re-ducing side effects,and improving patient compliance.In this review,we summarize the pathophysiolog-ical characteristics of UC and the most recent status of numerous nanodrug delivery systems based on different targeting mechanisms in treating UC.Oral,intravenous,and rectal drug delivery nanoparticles targeting the colon are discussed,which can provide ideas for the design of colon-targeting nanoparticles for the treatment of colon diseases,especially for the treatment of UC.Last but not least,we provide a glimpse into the future of colon-targeted delivery systems,as well as future advancements in the field.
      原文链接:
    • 万方数据
    • 维普

    Heptamethine cyanines in bioorthogonal chemistry

    Yuanyuan LiaoYuting LiangYurou HuangXiaoyan Zeng...
    131-137页
    查看更多>>摘要：Due to their excellent fluorescence properties and biological function,cyanine dyes have been widely ap-plied in biological imaging.Heptamethine cyanine(Cy7)dyes,as a type of classic near-infrared(NIR)flu-orescent dyes,are considered as one of the effective fluorescent tools in the living organisms due to their good biocompatibility and very low background interference.Bioorthogonal reactions performed in living cells and tissues have developed by leaps and bounds in recent years.The NIR fluorescent labeling tech-nique involving cyanine has attracted widespread attention.This review summarizes their recent applica-tion in the field of bioorthogonal imaging,mainly concluding Cy7-type dyes,labeling strategy,bioimaging application,etc.We expect this work can provide some helps for the studies of NIR bioorthogonal reac-tion in vivo.
      原文链接:
    • 万方数据
    • 维普

    Nanozyme-activating prodrug therapies:A review

    Yudong WuWujun ChenChao WangDongming Xing...
    138-150页
    查看更多>>摘要：Enzyme prodrug therapies(EPTs)have been intensively explored as attractive approaches to selective ac-tivation of systemically administered benign prodrugs by the exogenous enzymes or enzymes expressed at the desired target site,thus achieving localized,site-specific therapeutic effect.Many effective strate-gies(e.g.,antibody-,viral-,gene-,as well as polymer-directed EPT)have been developed for enzyme lo-calization to locally activate systemically administered benign prodrugs.Nevertheless,intrinsic limitations(e.g.,complex intracellular environment and catalyst instability)make the practical application of EPT strategies a task that presents itself as highly challenging.As a promising alternative to natural enzyme,nanozyme has attracted substantial attention since its discovery in 2007,mainly due to the advantages of robust catalytic activity,high stability,low cost,and facile synthesis.Recently,nanozyme-activated pro-drug strategies bring a new opportunity for targeted therapy,referred to as nanozyme-activating prodrug therapies.This review focuses on recently reported nanozyme-activated prodrug strategies,aiming to pro-vide some new insights into the potential applications in site-specific drug synthesis.
      原文链接:
    • 万方数据
    • 维普

    Advanced nano drug delivery systems for neuroprotection against ischemic stroke

    Chenchen XieJun LiaoNing ZhangYuhan Sun...
    151-162页
    查看更多>>摘要：Ischemic stroke(IS)represents a significant threat to brain health due to its elevated mortality and dis-ability rates.The efficacy of small-molecule neuroprotective agents has been impeded by challenges asso-ciated with traversing the blood-brain barrier(BBB)and limited bioavailability.Conversely,advanced nano drug delivery systems hold promise for overcoming these obstacles by facilitating efficient transportation across the BBB and maintaining optimal drug concentrations.This review aims to explore advanced neu-roprotective nano drug delivery systems as a means of effectively administering neuroprotective agents to the brain using pharmaceutical approaches in the treatment of IS.By examining these systems,re-searchers and clinicians can gain valuable insights and innovative concepts,illuminating the potential of advanced neuroprotective nano drug delivery systems.Leveraging these advancements can drive the progress of pioneering and efficacious therapeutic interventions for IS.
      原文链接:
    • 万方数据
    • 维普

    Drug delivery systems for colorectal cancer chemotherapy

    Wen ChenKun ShiYan YuPeipei Yang...
    163-175页
    查看更多>>摘要：Colorectal cancer causes the third most common type of malignant tumors with high morbidity and mor-tality.Chemotherapy is currently one of the most effective and common treatments for colorectal cancer.However,the poor water solubility of some chemotherapeutics,untargeted drug delivery,and the un-desirable systemic side effects of conventional treatment remain the major issues for colorectal cancer chemotherapy.Fortunately,drug delivery systems(DDS)based on biomaterials have been widely investi-gated and found to be capable of resolving those issues with good performance.Therefore,the main goal of this review is to summarize and discuss the progress and potential advantages of different DDS for colorectal cancer chemotherapy.We not only reviewed the nanocarriers used to improve the solubility of chemotherapeutics,including liposomes,micelles,and nanoparticles,but also discussed targeted DDS based on specific ligand-receptor recognition and tumor microenvironmental stimulus responses.Further-more,locally administered systems based on hydrogels and microspheres,which have been shown to increase drug accumulation at the tumor site while decreasing systemic toxicity,were also emphasized.DDS provides a good option for improving the efficacy of chemotherapy in the treatment of colorectal cancer.
      原文链接:
    • 万方数据
    • 维普

    Bone tissue engineering scaffold materials:Fundamentals,advances,and challenges

    Chang XuZhize LiuXi ChenYang Gao...
    176-186页
    查看更多>>摘要：Bone damage caused by trauma and tumors is a serious problem for human health,therefore,three-dimensional(3D)scaffolding materials that stimulate and promote the regeneration of broken bone tis-sues have become the focus of current research in the field of bone damage repair.To this regard,a preferential combination of materials and preparation techniques is considered crucial for the prepara-tion of advanced bone tissue engineering scaffolds to better facilitate the regeneration of broken bone.In this review,current research advances and challenges in bone tissue engineering scaffolds are discussed and analyzed in detail.First,we elucidated the structure and self-healing mechanism of bone tissue.Sub-sequently,the main applications of different materials,including inorganic and organic materials,in bone tissue engineering scaffolds are summarized.Moreover,we overview the latest research progress of the mainstream preparation strategies of bone tissue engineering scaffolds,and provide an in-depth analysis of the different advantages of each method.Finally,promising future directions and challenges of bone tissue engineering scaffolds are systematically discussed.
      原文链接:
    • 万方数据

    A review on g-C3N4 decorated with silver for photocatalytic energy conversion

    Ziyu PanWufan DingHanchun ChenHaodong Ji...
    187-196页
    查看更多>>摘要：Artificial photocatalytic energy conversion is considered as the most potential strategy for solving the in-creasingly serious energy crisis and environmental pollution problems by directly capturing solar energy.Therefore,high efficiency photocatalyst has drawn significant research attention in recent years.Due to the excellent electronic,optical,structural,and physicochemical performances,silver-based g-C3N4 have become promising photocatalysts.This review emphasizes the recent progresses and challenges on g-C3N4 decorated with silver for photocatalytic energy conversion.The extensive use of g-C3N4 decorated with silver in diverse photocatalytic reactions,including hydrogen evolution,pollutant degradation and carbon dioxide reduction,is also fully introduced.In addition,we propose the perspectives of g-C3N4 decorated with silver on photocatalytic applications.We hope that this review will shed some light on the photocatalytic energy conversion of g-C3N4 decorated with silver.
      原文链接:
    • 万方数据

    Towards catalytic reactions of Cu single-atom catalysts:Recent progress and future perspective

    Yitao ZhaoLei Tao
    197-207页
    查看更多>>摘要：One of the urgent and challenging topics in diversified sustainable energy conversion is the development of high-performance,low-cost,and well durable catalysts.Cu single-atom catalysts(SACs)have become promising catalysts for diversified sustainable energy conversion due to their capability to maximize the utilization efficiency,acquire modulated electronic structure and optimized binding strength with inter-mediates.In this review,we have provided an interview of the recent progress achieved in the field of electrocatalysis,photocatalysis,and heterogeneous reaction based on Cu SACs.Started by this review,we have summarized some advanced synthetic strategies for the construction of Cu SACs.Subsequently,the performance-improving strategies are discussed in terms of the coordination environments of the re-action center,reaction mechanism and selectivity,based on free energy diagram and electron structure analysis.Finally,the remaining issues,challenges,and opportunities of Cu SACs are also provided,afford-ing a perspective for future studies.This review not only offers us a deep understanding on the catalytic mechanism of Cu SACs for energy conversion,but also encourages more endeavors in prompting their practical application.
      原文链接:
    • 万方数据
    • 维普

    Review of MXenes as a component in smart textiles and an adsorbent for textile wastewater remediation

    Kaniz FarhanaKumaran KadirgamaAbu Shadate Faisal MahamudeRajan Jose...
    208-222页
    查看更多>>摘要：Two-dimensional(2D)MXenes have emerged as an archetypical layered material combining the proper-ties of an organic-inorganic hybrid offering materials sustainability for a range of applications.Their sur-face functional groups and the associated chemical properties'tailorability through functionalizing MX-enes with other materials as well as hydrophilicity and high conductivity enable them to be the best suc-cessor for various applications in textile industries,especially in the advancement of smart textiles and remediation of textile wastewater.MXene-based textile composite performs superb smartness in high-performance wearables as well as in the reduction of textile dyes from wastewater.This article critically reviews the significance of MXenes in two sectors of the textile industry.Firstly,we review the improve-ment of textile raw materials such as fiber,yarn,and fabric by using MXene as electrodes in supercapaci-tors,pressure sensors.Secondly,we review advancements in the removal of dyes from textile wastewater utilizing MXene as an absorbent by the adsorption process.MXene-based textiles demonstrated superior strength through the strong bonding between MXene and textile structures as well as the treatment of adsorbate by adsorbent(MXene in the adsorption process).We identify critical gaps for further research to enable their real-life applications.
      原文链接:
    • 万方数据
    • 维普